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Are Hansen solubility parameters available for inorganic salts or ionic molecules (e.g. potassium oleate, potassium stearate, sodium dioctyl sulfosuccinate (AOT), sodium dodecyl benzol sulfonate (SDBS), sodium dodecyl sulfate (SDS), sodium oleate, sodium stearate)?

For describing a water phase, the solubility parameters of water-soluble salts are needed. For describing ionic surfactants, the solubility parameters of organic ions are needed.

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  • $\begingroup$ AFAIK there is yet no systematic studies of HSP for inorganic salts and organometallic species available. I suspect you would need to do research for each compound of interest. For example, lithium stearate is mentioned in doi.org/10.1016/0021-9797(73)90201-4. $\endgroup$ – andselisk Feb 2 at 14:40
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Until now, I found the following.

Bustamante, P.; Peña, M. A.; Barra, J.: The modified extended Hansen method to determine partial solubility parameters of drugs containing a single hydrogen bonding group and their sodium derivatives: benzoic acid/Na and ibuprofen/Na. Int. J. Pharm. 194 (2000) 117-124:
benzoic acid/Na, ibuprofen/Na

Barra, J.; Peña, M. A.; Bustamante, P.: Proposition of group molar constants for sodium to calculate the partial solubility parameters of sodium salts using the van Krevelen group contribution method. Eur. J. Pharm. Sci. Off. J. Eur. Fed. Pharm. Sci. 10 (2000) (2) 153-161:
benzoic acid/Na, diclofenac/Na, ibuprofen acid/Na, p-aminobenzoic acid/Na, salicylic acid/Na

Kitak, T.; Dumicic, A.; Planinšek, O.; Šibanc, R.; Srcic, St.: Determination of Solubility Parameters of Ibuprofen and Ibuprofen Lysinate. Molecules 20 (2015) (12) 21549-21568:
ibuprofen/Na

There are almost 20 sodium salts in the HSPiP software.

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