I am looking to attempt an extraction of an organic compound that had just been prepared using a Friedel-Crafts acylation. The compound was prepared in MDC (~20 mL in total). After the reaction, the organic compound was poured into ~20 mL of ice-cold distilled water. The protocol I am referring to states
"The reaction mass was cooled and water was added slowly under stirring condition. Product was extracted in MDC (12 X 2) and washed with water followed by treating with saturated sodium chloride solution (20 mL) ... "
I don't want to make any inferences as to what this means since I am new to synthetic lab work, but my guess is that it means 2 portions of 12 mL of MDC were used to separate the compound from the aqueous phase. I am not sure why they follow this by washing with water unless I am interpreting what "Extracted in MDC (12 X 2)" means. Similar sections in the paper include a little more detail that confirms my original speculations regarding what is meant by (12 X 2), but it still does not make sense to me why this would be followed by washing with water and not skip immediately to washing with a saturated NaCl solution. Here is the DOI to the paper: https://doi.org/10.1016/j.bmc.2018.05.016. The section I am looking at is 2.1.4.