What methods are available for the C-3 formylation of 2-phenylindole?


closed as off-topic by Mithoron, Mathew Mahindaratne, Todd Minehardt, Tyberius, Poutnik Aug 16 at 14:17

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  • $\begingroup$ Phenyl is hardly bulky... $\endgroup$ – Mithoron Aug 1 at 18:37
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    $\begingroup$ Vilsmeier-Haack formylation is my first choice. See, Organic Reactions, volume 49. $\endgroup$ – user55119 Aug 1 at 19:33
  • $\begingroup$ The Duff reaction will also do this, but Vilsmeier-Haack is utterly standard. See pubs.acs.org/doi/10.1021/jo00987a009 $\endgroup$ – Waylander Aug 1 at 22:08
  • $\begingroup$ @user55119 by editing the question into a bland statement of how-does-it-work, you've made it an eligible candidate for homework closure. Please edit it back and apply a few grammar fixes instead. (I prefer not to since I can't see images) $\endgroup$ – M.A.R. Aug 14 at 19:42
  • $\begingroup$ @M.A.R.: The edit was intended to clarify what the OP was trying to ask.. If it is bland, I presume you have that privilege to revert to the original.. I won't be offended. I agree that it should be closed. $\endgroup$ – user55119 Aug 14 at 20:45