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I am going to synthetise isopropyl salicylate. From what I have read on phillysim.org (pdf) the formation of ethyl salicylate can be catalyzed by boric acid. I could use sulfuric acid but it would be much more convenient with boric acid. Ethanol and isopropanol have some differences, so I am not sure if it works for both of them.

Has anyone tried this? Does it work? Would it be better to just use sulfuric acid?

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  • $\begingroup$ According to link.springer.com/article/10.1007%2FBF01178939 It looks like it works, but probably the "milder" conditions required by sulfuric acid (plus its dehydrating power) make it preferable. A secondary alcohol (isopropanol) should not be a problem anyway $\endgroup$ – The_Vinz Jun 4 at 18:29

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