While reading some notes about Glucose and its various projections:
- Fischer Projection: 4 chiral centres
- Haworth Projection: 5 chiral centres
My doubt is that is there any (specific) method (practical) to ascertain the number of chiral centres in both the forms.
I know that more than 99.5% of glucose exists as Haworth Projection - Closed Ring Structure and hence Linear - Fischer Projection practically does not exist.
But it (linear ie open chain glucose) could be always isolated though difficult.