A friend of mine, final year PhD, and I, final year Bachelor, are focusing on hydroamination reactions. In particular those with secondary amines and substituted alkenes. The reaction in particular is given by
Intermolecular hydroamination of unactivated alkenes with substituted secondary amines seems to be quite difficult. However, additions of cyclic and acyclic secondary alkyl amines to a wide range of alkenes with anti-Markovnikov regioselectivity have been reported. Some of those reactions are redox-neutral and occur readily at room temperature under visible light irradiation.
Our question is: what would be an applicable catalyst for this particular reaction (secondary amine + substituted alkene) and what reaction conditions would be necessary?
Thanks in advance!
The reaction may also concerns the primary amine,
However, we would like to keep the substituted alkene substrate as it is.