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I'm not a specialist but I'd like to get into meaning of what is written in some articles. In the sentences:

"The large numbers of salt bridges and hydrogen bonds in the protein interface account ..."

"Alanine scanning mutagenesis have showed that only some of the amino acids of the interface account ..."

what is "account" stands for? As long as I understand, an "interface" is a protein part/domain that contacts with another interacting protein. But what is an "interface account"?

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    $\begingroup$ I'm voting to close this question as off-topic because it's a not about chemical nomenclature, but common word. $\endgroup$ – Mithoron Sep 10 '18 at 18:03
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    $\begingroup$ Account seems to be used as a verb here, but I can't tell without more context. $\endgroup$ – a-cyclohexane-molecule Sep 10 '18 at 20:32
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"Account" in this case is used as a verb.

The original paper for the second quote appears to be a PLoS One article, and the exact quote is

Alanine scanning mutagenesis have showed that only some of the amino acids of the interface account for the binding free energy.

We could equivalent rewrite this as

Alanine scanning mutagenesis have showed that only some of the amino acids of the interface are responsible for the binding free energy

or

Alanine scanning mutagenesis have showed that only some of the amino acids of the interface contribute significantly to the binding free energy

I haven't looked at the first quote, but I suspect it's in a similar boat.

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  • $\begingroup$ It does make sense. Thank you for the answer. $\endgroup$ – user619271 Sep 10 '18 at 18:04

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