Timeline for Reaction between carboxylic acids and amines
Current License: CC BY-SA 4.0
5 events
| when toggle format | what | by | license | comment | |
|---|---|---|---|---|---|
| Feb 4, 2019 at 20:44 | vote | accept | H.Linkhorn | ||
| Feb 4, 2019 at 17:12 | comment | added | H.Linkhorn | So, does that mean that when you are forming polyamides, a salt if formed first and then you have to heat the mixture to drive off the water leading to polymerisation? | |
| Feb 4, 2019 at 16:16 | comment | added | Jan | @H.Linkhorn In introductory chemistry, you would probably use heat. The salt forms immediately at any temperature at which the suitable solution is liquid. For the condensation reaction to occur, the activation barrier must be overcome which is easily achieved by heating up. Another one is removal of water e.g. using molecular sieves. In preparative chemistry, you would usually not use the actual acid but an activating ester (e.g. phenyl thiocarboxylate) or in situ activator such as DCC. | |
| Feb 4, 2019 at 14:30 | comment | added | H.Linkhorn | So what is it exactly about the “harsher conditions” that make the amine act as a nucleophile and not a base? | |
| Feb 4, 2019 at 2:13 | history | answered | Jan | CC BY-SA 4.0 |