The scientific study of chemical processes in living organisms, including, but not limited to, living matter.

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2
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2answers
167 views

Are all anomers diastereomers?

I am told that all anomers are diastereomers. I think this is BS. If there is a carbohydrate with only one chiral center, then changing the configuration of the anomeric carbon gives us enantiomers. ...
4
votes
3answers
750 views

what does the '-1' superscript mean in units?

For example, the rate of a chemical reaction can be expressed in $\mathrm{mol}/\mathrm{L}^{-1}/\mathrm{sec}^{-1}$. Why is it '-1' and not, say, '-2'? Does it change the meaning if the minus is removed ...
0
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0answers
15 views

How to plot standard curve using D-Galactouronic acid

I wanted to calculate the Pectinase enzyme activity. so how can I plot standard curve using D-galactouronic acid ? also is it possible using glucose ?
0
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0answers
21 views

Software for predict physical and chemical properties [closed]

Are there something soft for predicting properties (except for Openbabel)?
1
vote
1answer
37 views

In water, will sucrose be hydrolysed by water to form glucose and fructose molecules?

If I dissolve sucrose sugar ($\ce{C_12H_22O_11}$) in water, would the water readily hydrolyse the sucrose sugar to form glucose and fructose sugars?
4
votes
1answer
33 views

How does aminoguanidine interfere with the formation of advanced glycation endproducts?

This says that aminoguanidine interferes with the formation of advanced glycation endproducts (AGEs) through interacting with 3-deoxyglucosone. But how does it interact with 3-deoxyglucosone that ...
2
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0answers
15 views

Why is cytosine far more vulnerable to hydrolytic deamination than both adenosine and guanosine?

Here's the source for the claim (the half-life is 340 years at 298 K, which is much smaller than that of adenosine and guanosine).
0
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0answers
14 views

Why is LDL more easily oxidized/damaged than HDL?

By LDL and HDL, I mean the lipoproteins that carry cholesterol. Oxidation of LDL ultimately contributes to heart disease.
1
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0answers
22 views

Why is N7 of guanine so vulnerable to addition via alkylating agents? [closed]

Especially compared to N7 of adenine and the other nitrogen atoms of guanine?
1
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1answer
28 views

Why are so many different organophosphates able to deactivate acetylcholinesterase?

From sarin to http://en.wikipedia.org/wiki/Tricresyl_phosphate, there are such a huge diversity of them that can do it. What's so special about the simple organophosphate group that makes them able ...
0
votes
1answer
42 views

Explicit differential equation based model of protein folding

I am an applied mathematician interested in the dynamics of potential systems - i.e., systems with multiple unique energy minima. One of the best examples of such systems are protein folding ...
1
vote
0answers
18 views

Is catechol (o-dihydroxybenzene) more prone to auto-oxidation than p-dihydroxybenzene or m-dihydroxybenzene?

And if so, why? Apparently, both dopamine and caffeic acid are prone to auto-oxidation. So I wonder if it's a property of o-dihydroxybenzenes in general.
8
votes
1answer
100 views

How can a protein folding transition state have zero lifetime?

I'm doing a module on my Biochemistry course looking at protein folding, and in a discussion of [folding] transition states I was a little confused at the thought of a zero-lifetime transition state - ...
3
votes
0answers
27 views

How to analytically quantify a chemical's potential to intercalate DNA?

This shows that polyphenols (like quercetin) have the potential to intercalate DNA, but at potency 100x less than that of ethidium bromide. How does one analytically measure/quantify "100x weaker"? ...
0
votes
1answer
29 views

How does sulbutiamine work in the same way as thiamine, even if it doesn't have a thiazole ring?

So sulbutiamine is said to be a thiamine substitute. Yet - it doesn't contain the thiazole ring that's so important for many of thiamine's functions.
0
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0answers
23 views

What are the metabolites and method of action of Contrave, Belviq or Phentermine?

The SE staff spurred me into wondering about diet pills. What are the metabolites and method of action of Contrave, Belviq or Phentermine?
0
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0answers
38 views

Algorithm that calculates damage from adrafinil?

is there such a thing that calculated damage of adrafinil based on dosage? lets say i take a dosage of 100mg/ day for 100 days, what would the affect be? how much % of my liver will be damaged? Do ...
1
vote
1answer
39 views

ATP break down and energy release?

I have a very basic question. Energy is absorbed to break bonds. Bond-breaking is an endothermic process. Energy is released when new bonds form. Bond-making is an exothermic process. But ATP breaks ...
0
votes
0answers
26 views

How do I figure out where velocity declines?

I am stumped on one question on my biochem practice problems. We went over all of them today but my whole group was unable to figure out how to properly set up the equations to calculate the change in ...
1
vote
1answer
29 views

What trends affect hydrophobicity in amino acids?

I was wondering if the length of the carbon backbone affects hydrophobicity of amino acids (i.e. longer carbon backbone of side group = less polar = more hydrophobic).
0
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0answers
17 views

Procedure of Hydrate Lab

How do you find the formula of a hydrate when given an impure substance? Is there any procedure to find this out in a laboratory setting?
0
votes
1answer
32 views

How does life choose it's nominal temperature preferences?

If all life relies on water, and water freezes at 32F and boils at 212F. Then why isn't the nominal temperature for life 122F? 122F will literally kill some animals, including us. Do our ...
2
votes
0answers
20 views

Delta G values for Pyruvate--> Alanine vs. Oxaloacetate -> Aspartate ->Asparagine

What are the delta G values for the mammalian (human) biosynthesis of alanine from pyruvate, and for the conversion of oxaloacetate to asparagine? (assuming no particular cellular restriction or other ...
7
votes
0answers
179 views

Influence of Temperature on Biochemical Reactions

Short question How (quantitatively speaking) does temperature influences rate of decay of proteins? I am looking for some general number/function, the influence of temperature on an average protein. ...
0
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0answers
23 views

Book recommendations for protein structure refinement

I’m an undergraduate Chemistry student and I’m currently writing my dissertation about semi-empirical methods, particularly PM7, applied to protein structure refinement from X-ray structure. Could you ...
1
vote
0answers
51 views

What is the formula for migration rate of DNA in agarose gel electrophoresis?

Let's consider a typical agarose gel electrophoresis experiment. An appropriate quantity (not so much that it is overloaded, but not so little that it cannot be visualized) of linear DNA pieces with ...
2
votes
1answer
29 views

Predicting 260/280 of DNA or RNA from sequence?

I asked this in biology, but I think they don't want to deal with the chemistry behind UV-Vis. My question has to do with the Poly A tails on mRNA. I've been doing in vitro transcription and tailing ...
2
votes
3answers
71 views

Which software is suitable to calculate the root mean square deviation between two protein structures?

I need to compute the root mean square deviation (RMSD) between two protein structures: the X-ray determined protein structure and the MOPAC optimized structure. Which software do you suggest?
4
votes
2answers
102 views

What happens if you autoclave HEPES?

Many molecular biology protocols advice against sterilizing HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) solutions by autoclave. Supposedly, HEPES is heat labile, and the high ...
1
vote
0answers
12 views

Enzyme Assay - pectinase

I am working on Enzyme Assay.I assayed the enzyme in different buffers from $pH\ 1-12.5$ However,the enzyme has good activities starting from $pH\ 1-10.5$ Is that possible to have enzyme activity in ...
3
votes
2answers
49 views

Using Hydrates as a skin moisturizer

I was just in my AP Chemistry class earlier today learning about hydrates and their properties. It occurred to me that a compound with so much water could aid in moisturizing the skin. Is this a valid ...
0
votes
0answers
34 views

What is the reason for particular reaction rates for oxidation, combustion, and metabolic reactions?

We are currently working with reaction rates in Chemistry. I need some help with a question for the upcoming test. "Give examples of phenomenons or products and explain why they have a certain ...
3
votes
1answer
73 views

What element or compound could be used to create a more base ocean?

The ocean is becoming acidic. This is not a natural evolutionary change but happens through human negative effect on the environment. What element or compound could be used to create a more base ...
8
votes
3answers
523 views

Biological Consequences of Asteroid Mining—Death by Isotope?

It's been documented that NASA hope to capture an asteroid in 2025, and have subsequent aims to mine that asteroid. If if this is successful, we would expect other asteroids to be mined in the future. ...
3
votes
1answer
37 views

How can I measure carcinogenic risks of an M-ENDO-Agar LES substrate after heat destruction?

I'm about to conduct a study of possible toxic traces from the substance M-ENDO-Agar LES in substrate after destruction with heat (I think it is 160℃) for 180 minutes. The substance is carcinogenic. ...
0
votes
0answers
25 views

Why are non-polar hydrogens neglected in protein-drug binding studies?

Why are (Non-polar) Hydrogen generally neglected in a protein-ligand (or drug) binding energy calculation? They do have charge and mass. Doesn't that affect the free energy calculation?
3
votes
2answers
70 views

Mercury brain half-life

If have read conflicting reports on the half-life of mercury in the brain. I would like to hear some estimates from this community. I am also wondering how long chelation therapy would take to remove ...
1
vote
0answers
25 views

Mercury binding agents which cross the blood brain barrier

The two substances I have come across are cilantro and lipoic acid. How effective would either of them be? Are there any other agents known which produce the desired results?
1
vote
0answers
18 views

removing mercury from the brain

I have conducted many searches on this subject with regards to agents which cross the blood brain barrier. I have read about lipoic acid. Is anybody on here aware of any studies or findings which show ...
1
vote
2answers
36 views

Mercury vapor release from amalgam fillings

What would cause vapour release from elemental mercury? Would it be pressure, friction... could one stop the vapour release through cooling the mercury?
2
votes
1answer
69 views

About all the pop drinks being sold

Regarding chemical synergies I read if someone ingests various product with sodium benzoate (forgive spelling) like the MANY soft drinks that exist ; AND if one has had some quantity of vitamin C ...
8
votes
1answer
316 views

What are these crystals on my champagne cork?

I opened up a bottle of champagne that was left in a wine cooler for approx. 8 years. To my astonishment there were small crystals at the underside of the cork. The crystals are colorless, odorless ...
3
votes
1answer
29 views

What makes sulfur-containing compounds such good antioxidants?

Many sulfur-containing compounds (like glutathione and cysteine groups) have high antioxidant activity. Why?
1
vote
1answer
49 views

Psychoactive ingredients in this soap?

Could any ingredients from this product be psychoactive in some people, if the are sensitive to them? https://www.lush.co.uk/products/honey-i-washed-kids I have found the product to be relaxing as ...
1
vote
0answers
32 views

Bohr Effect - related to H+ only?

Would I be correct in saying that the Bohr effect is ONLY related to the concentration of [H+] in the tissues. Obviously the concentration of carbon-dioxide can contribute to this concentration by ...
2
votes
1answer
62 views

Why is the deprotonated form of dopamine more reactive than the protonated/neutral form of dopamine?

See this (from the Wikipedia article on dopamine): Dopamine, like most amines, is an organic base. At neutral or acidic pH levels it is generally protonated. The protonated form is highly ...
5
votes
2answers
69 views

Does vinegar neutralize the strongly basic compounds in cement?

I have heard that washing one's hands with vinegar is effective in neutralizing the strong bases in cement and is more effective than water. I want to know how cement burns and what bases are ...
0
votes
0answers
18 views

What happen when there is no salt bridge in microbial fuel cell?

I wonder if there is no salt bridge on microbial fuel cell, Are there have the same amount of current or none?
1
vote
1answer
58 views

Greater entropy: an atom or macromolecule?

A question that appeared on my last chemistry exam was : Which of the following has greater entropy A) An atom B) A macromolecule The question doesn't specify anything else(i.e. type/size ...
2
votes
1answer
22 views

Quaternary ammonium anti-microbials

Also good against fungi, amoeba, and enveloped viruses,[7] quats are believed to act by disrupting the cell membrane. Quaternary ammonium cleaners have long-alkyl substituent chains. Why is this ...